This is going to be harder than most years, because we're not actually getting an E3, and the streaming events that are replacing it are all through June and into July. Here's the schedule we know so far:
IGN's Summer of Gaming - Throughout June
Media Indie Exchange's Guerrilla Collective - June 6-8
EA Play - June 11
Ubisoft Forward - July 12
Microsoft's Inside Xbox 20/20 - July
Sony is also widely rumored to be doing a PS5 event in early June, and Nintendo is expected to do a Direct, although there's no known date for that.
So, with all of that said, here are my predictions:
Microsoft
Clearly there's going to be information about the Xbox SEX, but specifically I'm expecting a release date announcement, probably for mid to late November. Halo Infinite as a launch game (again, obviously), and a bunch of gameplay from that, as well as from some big third party titles. Maybe something like Assassin's Creed Valhalla running on SEX, or Cyberpunk. Then a montage trailer with short clips of a bunch of different games.
Sony
Again, PS5 news is obvious, I'm expecting a release date also in mid to late November, either one week before or after Xbox. Announcements of PS5 versions of Ghost of Tsushima and TLoU2 (not just back compatibility for those games). Announcement of whatever their back compatibility program is, probably it will run PS4 games, but I'm not expecting anything as involved as Microsoft's smart download system or whatever they're calling it, just straight bc, possibly with performance/resolution enhancements over PS4 Pro like what Pro does with base PS4. We'll also see at least one 1st party launch title that we haven't heard about yet. They'll show some big third party game on PS5, possibly Valhalla or Cyberpunk, whichever MS doesn't have.
Nintendo
Animal Crossing. BotW2. Other insane shit no one can predict.
EA
Some info on the next Dragon Age, but it won't be coming this year. Lots of Apex. Remastered Mass Effect trilogy.
Ubisoft
Valhalla, obviously. More about Watch Dogs Legion, which won't be coming out this year. And I'm throwing out a hail Mary for a new Splinter Cell.
What's everybody else think/expect?