I just watched all six of the currently available episodes for Amazon's version of The Tick. I like this franchise in general. The comics are really funny, I remember liking the old cartoon, and I even bought the short-lived Warburton series on DVD. This new version is an interesting departure from the norm. It is still a comedy, but it feels like they're trying to take it more seriously, probably as a result of the popularity of the Marvel and DC movies and tv shows. Tick himself is still a complete buffoon without a doubt, and is the closest to his original version. Unsurprisingly, he's also the funniest. Arthur is still the straight man, but the show seems to put more focus on the negative impact the superhero business is having on his life and his relationships.
There aren't many other comic characters so far, but I like the new original heroes and villains they've come up with. Ultimately, the biggest difference between this version and previous versions is that while before, The Tick was one part of a crazy world full of loonies. Here, the world is treated fairly realistically outside of the presence of heroes and villains, but The Tick himself is just as goofy and invulnerable as ever.