This hardly coincides with what they usually say. Male default Shepard is on all advertising and they specifically say your Shepard dying in ME2 is not canon. So yes, there certainly is a canon play-through.
The only canon is the stuff that happens no matter what (like becoming a Spectre, joining Cerberus, etc), and the not-dying-in-the-suicide-mission thing. Outside of that there's no "canon" as far as game events go. I've read/heard that in numerous Bioware interviews (having trouble finding a link atm, will follow up when I do).
Default Shep != canon Shep.