But if your primary opposition to most government programs is "it's illegal" then something that's unambiguously legal wouldn't bother you.
Re: the healthcare law, I think it's probably way outside the bounds of what the Commerce Clause was ever intended to mean, but that it's within the Commerce Clause as it's been interpreted by the courts over the centuries. If I were the USSC deciding the issue with a completely blank legal history, then I would say no fucking way is that legal, but if I were the USSC deciding the issue with legal precedent as it exists now (or as I'm aware of it existing, I haven't exactly done huge amounts of research into this issue) then I'd say it's legal.
So then from a legal standpoint the question comes down not so much to political alignment as to your theory of constitutional interpretation (though often that lines up with politics fairly well). If you're primarily concerned with the intent of the framers then you're probably going to say that this law is illegal, if you're primarily concerned with established precedent then you could go either way (I'd say it's legal, but it does involve some inferential leaps that not everyone might be willing to make), and then if you look on the constitution as a fully living document then you could also go either way depending on lots of things.