I think that depends entirely on how well ME3 does on Wii U. And given the fact that I don't think it's going to do well because the majority of Wii U owners interested in playing it likely played it in the past 9 months on a different system. Still, I think games like ME3, AC3, and Arkham City were important for Nintendo to have, even if no one's playing them. Having those games says a lot about the system and what Nintendo fans can (hopefully) expect.